Objective: This study aimed to examine the relationship between
intolerance of uncertainty (IU), psychological resilience (PR), and
quality of life (QoL) in patients with obsessive-compulsive disorder
(OCD).
Method: A total of 144 participants (72 patients with OCD and 72
matched healthy controls) were included. Participants completed the
Intolerance of Uncertainty Scale (IUS), the Resilience Scale for Adults
(RSA), the Short-Form 36 (SF-36), the Hamilton Anxiety Rating Scale
(HARS), the Hamilton Depression Rating Scale (HDRS), and the Yale-
Brown Obsessive Compulsive Scale (Y-BOCS).
Results: The groups were matched for age, gender, and socioeconomic
status (p>0.05). The OCD group had significantly higher IU scores and
lower QoL scores across all SF-36 domains compared to controls. In the
OCD group, all QoL subscales showed a significant negative correlation
with total IUS scores (strongest for vitality: r=-0.676, p<0.001) and
a significant positive correlation with total RSA scores (strongest for
vitality: r=0.619, p<0.001). Regression analyses indicated that PR,
illness duration, and symptom severity (Y-BOCS) were significant
predictors of QoL, explaining 15.9% to 55.3% of the variance in key
mental health-related QoL domains.
Conclusion: QoL in OCD patients is significantly impaired compared
to healthy individuals. This impairment is strongly associated with
higher IU, lower psychological resilience, and greater symptom severity.
Keywords: Intolerance of uncertainty, obsessive compulsive disorder,
psychological resilience, quality of life